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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCA2 All Species: 10.61
Human Site: S2347 Identified Species: 19.44
UniProt: Q9BZC7 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BZC7 NP_001597 2435 269873 S2347 V L G I E D Y S V S Q T T L D
Chimpanzee Pan troglodytes XP_001152577 2346 264166 P2257 D L L P D L N P V E Q F F Q G
Rhesus Macaque Macaca mulatta XP_001117819 2476 273629 S2374 V L G I E D Y S V S Q T T L D
Dog Lupus familis XP_537788 2395 264756 S2299 V L G I E D Y S V S Q T T L D
Cat Felis silvestris
Mouse Mus musculus P41234 2434 270490 D2346 V G V L G I E D Y S V S Q T T
Rat Rattus norvegicus Q9ESR9 2434 270910 D2346 V G V L G I E D Y S V S Q T T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516009 2266 254238 N2179 V L K E K H R N M L Q Y Q L P
Chicken Gallus gallus XP_422330 2276 256293 S2189 I R I N F P G S L Q R E K H Y
Frog Xenopus laevis NP_001089022 2363 267334 P2273 K F I Q T N F P G S V Q R E K
Zebra Danio Brachydanio rerio NP_001139161 2268 254351 N2181 T L K E K H R N M L Q Y Q L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34358 1704 191394 V1617 R D M V V Q L V Q T R L P N S
Sea Urchin Strong. purpuratus XP_798273 1913 213253 Y1826 K A Y K C I G Y C P Q F D A L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84M24 1882 209045 P1794 L F R D G G I P L P I F A E W
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 35.1 96 82.2 N.A. 91 92.9 N.A. 39.1 35.7 36.5 37.7 N.A. N.A. N.A. 23.7 41.7
Protein Similarity: 100 52 96.6 86.1 N.A. 93.2 94.9 N.A. 55.7 53.5 54.7 54.5 N.A. N.A. N.A. 39 54.4
P-Site Identity: 100 20 100 100 N.A. 13.3 13.3 N.A. 26.6 6.6 6.6 20 N.A. N.A. N.A. 0 6.6
P-Site Similarity: 100 26.6 100 100 N.A. 26.6 26.6 N.A. 46.6 26.6 20 40 N.A. N.A. N.A. 20 6.6
Percent
Protein Identity: N.A. N.A. N.A. 26.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 42.6 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 0 0 0 0 0 0 8 8 0 % A
% Cys: 0 0 0 0 8 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 8 8 0 8 8 24 0 16 0 0 0 0 8 0 24 % D
% Glu: 0 0 0 16 24 0 16 0 0 8 0 8 0 16 0 % E
% Phe: 0 16 0 0 8 0 8 0 0 0 0 24 8 0 0 % F
% Gly: 0 16 24 0 24 8 16 0 8 0 0 0 0 0 8 % G
% His: 0 0 0 0 0 16 0 0 0 0 0 0 0 8 0 % H
% Ile: 8 0 16 24 0 24 8 0 0 0 8 0 0 0 0 % I
% Lys: 16 0 16 8 16 0 0 0 0 0 0 0 8 0 8 % K
% Leu: 8 47 8 16 0 8 8 0 16 16 0 8 0 39 8 % L
% Met: 0 0 8 0 0 0 0 0 16 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 8 8 16 0 0 0 0 0 8 0 % N
% Pro: 0 0 0 8 0 8 0 24 0 16 0 0 8 0 8 % P
% Gln: 0 0 0 8 0 8 0 0 8 8 54 8 31 8 0 % Q
% Arg: 8 8 8 0 0 0 16 0 0 0 16 0 8 0 0 % R
% Ser: 0 0 0 0 0 0 0 31 0 47 0 16 0 0 16 % S
% Thr: 8 0 0 0 8 0 0 0 0 8 0 24 24 16 16 % T
% Val: 47 0 16 8 8 0 0 8 31 0 24 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % W
% Tyr: 0 0 8 0 0 0 24 8 16 0 0 16 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _